“Intracoronary Fibrin-Specific Thrombolytic Infusion Facilities Percutaneous Recanalization of Chronic Total Occlusion,” Journal of the American College of Cardiology 46(5):793-798.Īllie, D. Infection-resistant compositions, medical devices and surfaces and methods for preparing and using sameĪnonymous “TNKase, Tenecteplase Recombinant”, Product Brochue by: Genetech, Inc., South San Francisco, CA, May 2000.Ībbas,Aa.E. M-EDTA pharmaceutical preparations and uses thereof Variants of tissue plasminogen activator, compositions and methods of use for sameĪpparatus for preparing animal feedstuff from cotton seed Method for removing fibrin sheaths from cathetersĮnhancement of thrombolysis with external ultrasound Tissue plasminogen activator glycosylation variants with improved therapeutic properties Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices Use of thrombolytic reagents for prevention of vascular disease Isoxazoline and isoxazole fibrinogen receptor antagonists Method and apparatus for intravascular ultrasonography Method for modifying the surface of an object Methods of treating or preventing thromboses Kit for flushing medical devices and method of preparationĬatheter flush solution and method for its useĪntimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof Implantable system with drug-eluting cells for on-demand local drug delivery Method and apparatus for intravascular two-dimensional ultrasonography Method and device for locating guidewire and treating chronic total occlusions Synergy between low molecular weight heparin and platelet aggregation inhibitors, providing a combination therapy for the prevention and treatment of various thromboembolic disorders Methods of thrombolytic organ treatment and repair METHODS AND KITS FOR FOR LOCKING AND AND DISINFECTING IMPLANTED CATHETERS Method of enhancing catheter patency using a citrate salt catheter lock solution Differences for this subset were significant (P less than 0.050) for the follo.PLASMINOGEN ACTIVATOR VARIANT FORMULATIONS Results showed an association of the more aggressive intermediate/high-grade B-cell NHL with a higher percentage of late-phase activated TIL-T and a progressive increase with the grade of malignancy: 10.29%, 23.25%, 33.87%, and 47.78% (means) for BLH and for low-, intermediate- and high-grade B-cell NHL, respectively. Two activated T-cell subsets were studied: acutely activated TIL-T (CD3+ CD25+ HLADr-) and chronically activated TIL-T (CD3+ CD25- HLADr+). Immunotyping of tissue-cell suspensions was done by three-color flow cytometry, which was complemented by immunocytology by using cytocentrifuged preparations. Future studies should determine if in vitro expansion and adoptive transfer of this subset of T cells results in tumor cytolysis.Īctivated tumor-infiltrating T lymphocytes (TIL-T) were quantitated prospectively in excisional biopsy specimens of 49 B-cell non-Hodgkin's lymphomas (NHL) of various grades and compared with eight benign lymphoid hyperplasias (BLH) to identify any potential difference in host T-cell response. We now report that this subset of lymphocytes has also acquired memory function. We previously reported an increase in activated-cytotoxic T cells in IG -HG B cell NHL. Although the differences in naive T cells were non-significant, the differences in memory T cells were significant between LG and IG and LG and HG NHL (both p <. Memory and total T cells progressively increased from LG toward IG and HG NHL while naive T cells simultaneously decreased. CD3+CD45R0-CD45RA+ (naive), CD3+CD45R0+CDRA- (memory) and total CD3+ T cells were compared in BLH, low grade (LG), intermediate (IG) and high grade (HG) B cell NHL. Memory T cells were quantitated by three color flow cytometry in cell suspensions from biopsy specimens of 34 B cell non-Hodgkin's lymphomas (NHL) and 10 benign lymphoid hyperplasias (BLH).
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